Now showing items 1-10 of 32
Breathlessness in advanced disease. 1: Definitions, epidemiology and pathophysiology.
This first in a two part unit on breathlessness in advanced disease defines the condition and discusses the epidemiology. It gives an overview of the complex pathophysiology that contributes to breathlessness.
Preoperative hematologic markers as independent predictors of prognosis in resected pancreatic ductal adenocarcinoma: neutrophil-lymphocyte versus platelet-lymphocyte ratio.
BACKGROUND: The objective of this study was to investigate whether the preoperative hematologic markers, the platelet-lymphocyte ratio (PLR), or the neutrophil-lymphocyte ratio (NLR) ratio are significant prognostic ...
Anti-TNF-alpha agents are less effective for the treatment of rheumatoid arthritis in current smokers.
OBJECTIVES: To assess if smoking status at the time of commencing an anti-TNF-alpha agent for rheumatoid arthritis (RA) reduces the likelihood of achieving at least a moderate response on the European League Against ...
Rheumatoid cachexia and cardiovascular disease.
Both cachexia and cardiovascular disease are strongly associated with rheumatoid arthritis (RA) and linked to the chronic inflammatory process. Typically, rheumatoid cachexia occurs in individuals with normal or increased ...
Tissue-advanced glycation end product concentration in dialysis patients.
BACKGROUND AND OBJECTIVES: Tissue-advanced glycation end products (AGE) are a measure of cumulative metabolic stress. Assessment of tissue AGE by skin autofluoresence (AF) correlates well with cardiovascular outcomes in ...
A review article on gastric volvulus: a challenge to diagnosis and management.
Acute gastric volvulus is a life-threatening condition, but its intermittent nature and vague symptoms may make diagnosis difficult. Imaging is usually only diagnostic if carried out when patients are symptomatic. The ...
Role of routine oesophago-gastroduodenoscopy before cholecystectomy.
INTRODUCTION: A proportion of patients do not get symptomatic relief after cholecystectomy because there is an overlap in the symptomology of biliary and gasroduodenal pathologies. In our unit all the patients are offered ...
Pigmented villonodular synovitis of second toe interphalangeal joint: Methods of imaging.
Pigmented villonodular synovitis is a rare proliferative disorder of the synovium of unknown aetiology. We present a case of pigmented villonodular synovitis in an unusual location, the interphalangeal joint of a toe, ...
Breathlessness in advanced disease. 2: Patient assessment and management.
This second of a two part unit on breathlessness addresses patient assessment and management, including common treatments. Interventions that can be taught to, and used independently by, patients and carers are explored.