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Risk profile in chronic kidney disease stage 3: older versus younger patients.
BACKGROUND: The prevalence of chronic kidney disease (CKD) increases with age, but its significance in older patients is uncertain and is regarded by some as part of 'normal aging'. Moreover, subjects ≥75 years are often ...
Circulating endotoxemia: a novel factor in systemic inflammation and cardiovascular disease in chronic kidney disease.
BACKGROUND AND OBJECTIVES: Translocated endotoxin derived from intestinal bacteria has a wide range of adverse effects on cardiovascular (CV) structure and function, driving systemic inflammation, atherosclerosis and ...
The impact of antihypertensive drug therapy on endotoxemia in elderly patients with chronic kidney disease
BACKGROUND AND OBJECTIVES: Endotoxin (ET) is recognized to cause adverse effects on cardiovascular (CV) structure. Circulatory translocation of gut bacterial ET is described in heart failure. Chronic kidney disease (CKD) ...