Now showing items 11-20 of 25
Determinants of arterial stiffness in chronic kidney disease stage 3.
BACKGROUND: Early chronic kidney disease (CKD) is associated with increased cardiovascular (CV) risk but underlying mechanisms remain uncertain. Arterial stiffness (AS) is associated with increased CV risk in advanced CKD, ...
Regional Variation in Acute Kidney Injury Requiring Dialysis in the English National Health Service from 2000 to 2015 - A National Epidemiological Study.
BACKGROUND: The absence of effective interventions in presence of increasing national incidence and case-fatality in acute kidney injury requiring dialysis (AKI-D) warrants a study of regional variation to explore any ...
Anthropomorphic measurements that include central fat distribution are more closely related with key risk factors than BMI in CKD stage 3.
BACKGROUND: Body Mass Index (BMI) as a marker of obesity is an established risk factor for chronic kidney disease (CKD) and cardiovascular disease (CVD). However, BMI can overestimate obesity. Anthropomorphic measurements ...
Use of online conductivity monitoring to study sodium mass balance in chronic haemodialysis patients: prospects for treatment individualisation.
BACKGROUND: Failure to achieve isonatric haemodialysis (HD) drives an expansion of extracellular volume leading to increased interdialytic weight gain (IDWG). This may be a causative factor in the development of HD-induced ...
Chronic Kidney Disease in Primary Care: Outcomes after Five Years in a Prospective Cohort Study.
BACKGROUND: Chronic kidney disease (CKD) is commonly managed in primary care, but most guidelines have a secondary care perspective emphasizing the risk of end-stage kidney disease (ESKD) and need for renal replacement ...
A simple care bundle for use in acute kidney injury: a propensity score matched cohort study.
BACKGROUND: Consensus guidelines for acute kidney injury (AKI) have recommended prompt treatment including attention to fluid balance, drug dosing and avoidance of nephrotoxins. These simple measures can be incorporated ...
Assessment of proteinuria in patients with chronic kidney disease stage 3: albuminuria and non-albumin proteinuria.
BACKGROUND AND OBJECTIVE: Proteinuria assessment is key in investigating chronic kidney disease (CKD) but uncertainty exists regarding optimal methods. Albuminuria, reflecting glomerular damage, is usually measured, but ...
Impact of Compliance with a Care Bundle on Acute Kidney Injury Outcomes: A Prospective Observational Study.
BACKGROUND: A recent report has highlighted suboptimal standards of care for acute kidney injury (AKI) patients in England. The objective of this study was to ascertain if improvement in basic standard of care by implementing ...
International Criteria for Acute Kidney Injury: Advantages and Remaining Challenges.
Nicholas Selby and colleagues describe how the definition of acute kidney injury brings opportunities and challenges in identifying patients at higher risk of adverse outcomes.