Now showing items 1-10 of 35
Reducing catheter-associated urinary tract infections through best practice: Sherwood Forest Hospitals' experience.
A programme to standardise catheterisation practice was introduced in Sherwood Forest Hospitals NHS Trust in 2016, with the aim of reducing the incidence of catheter-associated urinary tract infections (CAUTIs). The ...
Down the drain and back up a drain
In this issue the paper by Aranega-Bou et al provides one more piece to the jigsaw of our understanding on drains and spread of organisms .
Non Invasive Ventilation: Case Study
(British Thoracic Society, 2019-02-18)
The Acute Non-Invasive Ventilation (NIV) team at King's Mill Hospital have been asked to collaborate with the British Thoracic Society (BTS) on a case study to share the results of our quality improvement transformation ...
Surgical lung biopsy for interstitial lung disease: when considered necessary, should these be done in larger and experienced centres only?
Surgical lung biopsy for ILD: higher volume centres may offer lower mortality, but data are only suggestive – we need more research, including into lower risk alternatives to conventional biopsy, to reduce risk for patients ...
The polyadenylation inhibitor cordycepin reduces pain, inflammation and joint pathology in rodent models of osteoarthritis.
Clinically, osteoarthritis (OA) pain is significantly associated with synovial inflammation. Identification of the mechanisms driving inflammation could reveal new targets to relieve this prevalent pain state. Herein, a ...
Trajectories of pain predict disabilities affecting daily living in arthritis.
PURPOSE: To examine the interplay between pain and disability in arthritis when adjusting for patient heterogeneity in pain progression. There is consistent evidence to suggest that people experience osteoarthritis ...
The impact of anxiety on chronic musculoskeletal pain and the role of astrocyte activation.
Anxiety and depression are associated with increased pain responses in chronic pain states. The extent to which anxiety drives chronic pain, or vice versa, remains an important question that has implications for analgesic ...
Molecular expression patterns in the synovium and their association with advanced symptomatic knee osteoarthritis.
OBJECTIVE: Osteoarthritis (OA) is a major source of knee pain. Mechanisms of OA knee pain are incompletely understood but include synovial pathology. We aimed to identify molecular expression patterns in the synovium ...
Characteristics and mortality of severe influenza cases treated with parenteral aqueous zanamivir, United Kingdom, October 2009 to January 2011.
BACKGROUND: Aqueous zanamivir solution, an investigational product, was provided by the manufacturer on compassionate grounds for parenteral administration to severe H1N1pdm09 influenza cases during the 2009 pandemic. ...
Core Health Outcomes in Childhood Epilepsy (CHOICE): Development of a core outcome set using systematic review methods and a Delphi survey consensus.
Objective: Establishing a core set of outcomes to be evaluated and reported in intervention trials aims to improve the usefulness of health research. There is no established core outcome set (COS) for childhood epilepsies. ...