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Manometry performed at indwelling pleural catheter insertion to predict unexpandable lung.
(2020-04)
Background: The finding of unexpandable lung (UL) at an early timepoint is of increasing importance in guiding treatment decisions in patients with malignant pleural effusion (MPE). Pleural manometry is the most common ...
Prognostic accuracy of emergency department triage tools for children with suspected COVID-19: The PRIEST observational cohort study.
(2020-09)
Objectives: Emergency department clinicians can use triage tools to predict adverse outcome and support management decisions for children presenting with suspected COVID-19. We aimed to estimate the accuracy of triage tools ...
Total versus partial knee replacement in patients with medial compartment knee osteoarthritis: the TOPKAT RCT
(2020-04)
Background: Late-stage medial compartment knee osteoarthritis can be treated using total knee replacement or partial (unicompartmental) knee replacement. There is high variation in treatment choice and insufficient evidence ...
Prospective validation of the RAPID clinical risk prediction score in adult patients with pleural infection: the PILOT study.
(2020-07)
Background: Over 30% of adult patients with pleural infection either die and/or require surgery. There is no robust means of predicting at baseline presentation which patients will suffer a poor clinical outcome. A validated ...
Shared genetic etiology of obesity-related traits and Barrett's esophagus/adenocarcinoma: Insights from genome-wide association studies.
(2020-02)
Background: Obesity is a major risk factor for esophageal adenocarcinoma (EA) and its precursor Barrett's esophagus (BE). Research suggests that individuals with high genetic risk to obesity have a higher BE/EA risk. To ...
Prognostic accuracy of emergency department triage tools for adults with suspected COVID-19: The PRIEST observational cohort study.
(2020-09)
Objectives: The World Health Organisation (WHO) and National Institute for Health and Care Excellence (NICE) recommend various triage tools to assist decision-making for patients with suspected COVID-19. We aimed to estimate ...
Experiences of using vedolizumab in the treatment of inflammatory bowel disease in the East Midlands UK - a retrospective observational study.
(2020-07-11)
Purpose: Clinical trials have demonstrated efficacy of vedolizumab in ulcerative colitis (UC) and Crohn's disease (CD). Further real-world data is needed to inform clinical practice. The primary outcome was to assess ...
Introducing artificial intelligence tools into clinical and non-clinical workflows, Evidence from the NHS Breast Screening Programme of staff and general population perceptions of and trust in the use of AI in this context and the implications for further testing and implementation.
(https://hsruk.org/conference-2020/presentations/understanding-service-use, 2020-06)
Background: The East Midlands Radiology Consortium (EMRAD) is a partnership of seven NHS trusts spread over 11 hospitals, covering more than five million patients in the East Midlands of England. In 2018, EMRAD formed a ...
A safe method to evacuate pneumoperitoneum during laparoscopic surgery in suspected COVID-19 patients.
(http://www.rcseng.ac.uk/publications/annals/, 2020-05)
The COVID-19 pandemic has introduced new challenges to surgery and protection of staff in the operating theatre. Aerosol and surface viability of the virus has been shown to last at least hours, with viability lasting days ...