Objectives. To investigate factors associated with joint damage in early RA, and how comorbid OA might influence patient assessment and outcomes. Methods. Baseline radiographs of hands and feet from 512 participants in the ...

OBJECTIVE: Osteoarthritis (OA) is a heterogeneous, multi-tissue disease. We hypothesised that different histopathological features characterise different stages during knee OA progression, and that discrete subgroups can ...

Background: Knee replacement surgery reduces pain for many people with osteoarthritis (OA). However, surgical outcomes are partly dependent on patients' moods, and those with depression or anxiety have worse outcomes. ...