Now showing items 1-3 of 3
Total versus partial knee replacement in patients with medial compartment knee osteoarthritis: the TOPKAT RCT
Background: Late-stage medial compartment knee osteoarthritis can be treated using total knee replacement or partial (unicompartmental) knee replacement. There is high variation in treatment choice and insufficient evidence ...
Contribution of nerves within osteochondral channels to osteoarthritis knee pain in humans and rats.
Summary Objectives Subchondral bone may contribute to knee osteoarthritis (OA) pain. Nerve growth factor (NGF) can stimulate nerve growth through TrkA. We aimed to identify how sensory nerve growth at the osteochondral ...
Investigating musculoskeletal health and wellbeing; a cohort study protocol.
Background: In an ageing population, pain, frailty and disability frequently coexist across a wide range of musculoskeletal diagnoses, but their associations remain incompletely understood. The Investigating Musculoskeletal ...